Accurate Supplements – CoQ10

CoQ10

 

Purchasing Supplements

When purchasing supplements reviewed on this web site and discussed with Dr. Ehlenberger, a discount on usual commercial pricing can be obtained by purchasing from Accurate Clinic’s online Supplement Store after acquiring the discount code from Accurate Clinic:

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(Option 2)

CoQ10 (Q-Best 100) – Thorne

Pricing

   CoQ10 100mg  (aka ubiquinone) #60

 

Exclusive crystal-free CoQ10 for superior absorption:

  1. proprietary formula with demonstrably better absorption over other CoQ10 forms, including dry powder, oil, nanoparticle, and liposomal preparations
  2. promotes normal cardiovascular function, enhances blood vessel function, and is an essential nutrient for cellular energy production*
  3. no chemical additives or titanium dioxide
  4. nearly three times better absorbed than ubiquinol

q-best-100-web

CoQ10

 CoQ10 is a nutrient that offers multiple health benefits as a supplement for many conditions. The education page regarding CoQ10 will be coming soon. In the meantime, please see below for information on Thorne brand CoQ10 and see further below for downloadable publications regarding CoQ10.

 

CoQ10 (Q-Best #100)

Ingredients

 One Gelcap Contains:

Calories 10
Calories from Fat 5
Total Fat 1 g
Cholesterol 0 mg
Total Carbohydrate 0 g
Protein 0.5 g
Coenzyme Q10 (aka ubiquinone) 100 mg

Other Ingredients: Gelatin (bovine), Purified Water, Glycerin (vegetable source), Lycopene and Turmeric (color) Gelcap, Conjugated Linoleic Acid, Flaxseed Oil, Soy Monoglycerides.

Contains ingredients derived from soy (soy monoglycerides).

Product Description (Thorne)

Q-Best is a proprietary, crystal-free preparation of coenzyme Q10 (aka ubiquinone) that consistently has demonstrated superior absorption over other forms of CoQ10, including dry powder, oil-based softgels, lipsosomes, micelles, and nanoparticle preparations.

 

All supplemental CoQ10 originates in a crystal (dry powder) form. However, this crystal form alone is not well absorbed because the crystals do not fully dissolve in the intestines and the body cannot absorb lipid crystals. When crystals are dissolved in a lipid-based delivery system (ie, oil-based softgels, liposomes, micelles, and nanoparticles), absorption is improved. However, there is still partial crystallization found in these preparations.

 

Q-Best provides CoQ10 in a fully dissolved, crystal-free, lipid-based form, allowing greater absorption by the intestinal mucosa. This is accomplished by a proprietary, tri-lipid delivery system. One lipid keeps the CoQ10 crystals fully dissolved at 10°C above body temperature; the second lipid keeps the CoQ10 crystals fully dissolved below body temperature; and the third lipid acts as a carrier molecule to facilitate absorption.

 

Clinical trials demonstrate superior absorption over dried powder preparations. In addition, a plasma CoQ10 bioavailability study observed absorption of Q-Best to be vastly greater than other forms of CoQ10, including oils suspension, nanoparticle, and liposomal preparations. This is why we believe Q-Best is the best CoQ10 formula available today.

 

Coenzyme Q10 functions as an intracellular antioxidant.* Due to its involvement in energy production within the cell, CoQ10 affects the function of all cells in the body, making it essential for the health of tissues and organs.* CoQ10 particularly benefits the most metabolically active cells: heart, immune system, gums, and the lining of the stomach and intestinal tract.* An adequate supply of intracellular CoQ10 is vital to the health of heart muscle.* CoQ10 supports normal heart rhythm and can help maintain already normal blood pressure.*

 

* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

 

Reference Publications

CoQ10 –  Overview

  1. CoQ10 – Brief Summary
  2. Coenzyme Q10 Therapy
  3. Impact of Oral Ubiquinol on Blood Oxidative Stress and Exercise Performance
  4. Therapeutic use of coenzyme Q10 and coenzyme Q10-related compounds and formulations. – PubMed – NCBI
  5. Primary and secondary coenzyme Q10 deficiency: the role of therapeutic supplementation. – PubMed – NCBI

 

CoQ10 – Ubiquinone vs Ubiquinol

  1. What’s the Difference Between Ubiquinone and Ubiquinol?

 

CoQ10 – Dosing and Safety

  1. Risk assessment for coenzyme Q10 (Ubiquinone). – PubMed – NCBI
  2. Safety assessment of coenzyme Q10 (Kaneka Q10) in healthy subjects: a double-blind, randomized, placebo-controlled trial. – PubMed – NCBI 

 

CoQ10 – Measurement of CoQ10 Levels

  1. Coenzyme Q10 – Is There a Clinical Role and a Case for Measurement?

 

CoQ10 – Cardiovascular

  1. Co-enzyme Q10 supplementation for the primary prevention of cardiovascular disease. – PubMed – NCBI
  2. Coenzyme Q10 supplementation reduces oxidative stress and increases antioxidant enzyme activity in patients with coronary artery disease. – PubMed – NCBI
  3. Effects of coenzyme Q10 supplementation on inflammatory markers (high-sensitivity C-reactive protein, interleukin-6, and homocysteine) in patients … – PubMed – NCBI
  4. Supplemental ubiquinol in patients with advanced congestive heart failure. – PubMed – NCBI
  5. The Relationship between Coenzyme Q10, Oxidative Stress, and Antioxidant Enzymes Activities and Coronary Artery Disease

 

CoQ10 – Central Sensitivity,  Oxidative Stress & Pain

  1. A newly identified role for superoxide in inflammatory pain. 2004
  2. Roles of Reactive Oxygen and Nitrogen Species in Pain – 2011

 

CoQ10 – Depression

  1. Lower plasma Coenzyme Q10 in depression – a marker for treatment resistance and chronic fatigue in depression and a risk factor to cardiovascular disorder in that illness

 

CoQ10 – Fatigue & Chronic Fatigue Syndrome

  1. Coenzyme Q10 deficiency in myalgic encephalomyelitis:chronic fatigue syndrome (ME:CFS) is related to fatigue, autonomic and neurocognitive symptoms… – PubMed – NCBI
  2. Does Oral Coenzyme Q10 Plus NADH Supplementation Improve Fatigue and Biochemical Parameters in Chronic Fatigue Syndrome?
  3. The role of mitochondrial dysfunctions due to oxidative and nitrosative stress in the chronic pain or chronic fatigue syndromes and fibromyalgia patients – 2013

 

CoQ10 – Fibromyalgia

  1. Benefits of Coenzyme Q10 | Fibromyalgia Natural Relief
  2. Can coenzyme q10 improve clinical and molecular parameters in fibro… – PubMed – 2013
  3. Coenzyme Q10 Regulates Serotonin Levels and Depressive Symptoms in Fibromyalgia Patients – 2013
  4. Effect of coenzyme Q10 evaluated by 1990 and 2010 ACR Diagnostic Criteria for Fibromyalgia and SCL-90-R – 2013
  5. Fibromyalgia: unknown pathogenesis and a “chicken or the egg” causa… – PubMed – 2012
  6. NLRP3 inflammasome is activated in fibromyalgia: the effect of coen… – PubMed – 2014
  7. Oral coenzyme Q10 supplementation improves clinical symptoms and re… – PubMed – 2012
  8. Oxidative stress and mitochondrial dysfunction in fibromyalgia. – PubMed – 2010

 

CoQ10 – Headaches (Migraine)

  1. A randomized, double-blinded, placebo-controlled, crossover, add-on study of CoEnzyme Q10 in the prevention of pediatric and adolescent migraine. – PubMed – NCBI
  2. Coenzyme Q10 deficiency and response to supplementation in pediatric and adolescent migraine. – PubMed – NCBI
  3. Improvement of migraine symptoms with a proprietary supplement containing riboflavin, magnesium and Q10 – Dolovent – 2015
  4. Open label trial of coenzyme Q10 as a migraine preventive. – PubMed – NCBI
  5. Oxidative Stress Correlates with Headache Symptoms in Fibromyalgia – Coenzyme Q10 Effect on Clinical Improvement

 

CoQ10 – High Blood Pressure

  1. Blood pressure lowering efficacy of coenzyme Q10 for primary hypertension (Review)

 

CoQ10 – Obesity

  1. Evaluation of antioxidant systems (coenzyme Q10 and total antioxidant capacity) in morbid obesity before and after biliopancreatic diversion

 

CoQ10 – Peripheral Neuropathy

  1. Diabetic neuropathic pain development in type 2 diabetic mouse model and the prophylactic and therapeutic effects of coenzyme Q10
  2. The effect of ubiquinone in diabetic polyneuropathy: a randomized double-blind placebo-controlled study. – PubMed – NCBI

 

CoQ10 – Statins

  1. Coenzyme Q(10) and statin myalgia: what is the evidence? – PubMed – NCBI
  2. Coenzyme Q10 Supplementation for the Treatment of Statin Induced
  3. Effect of coenzyme q10 on myopathic symptoms in patients treated with statins. – PubMed – NCBI
  4. Effects of coenzyme Q10 supplementation (300 mg:day) on antioxidation and anti-inflammation in coronary artery disease patients during statins therapy
  5. Effects of ubiquinone (coenzyme Q10) on myopathy in statin users. – PubMed – NCBI
  6. Pharmacogenetics of Statin-Induced Myopathy – A Focused Review of the Clinical Translation of Pharmacokinetic Genetic Variants

Emphasis on Education

 

Accurate Clinic promotes patient education as the foundation of it’s medical care. In Dr. Ehlenberger’s integrative approach to patient care, including conventional and complementary and alternative medical (CAM) treatments, he may encourage or provide advice about the use of supplements. However, the specifics of choice of supplement, dosing and duration of treatment should be individualized through discussion with Dr. Ehlenberger. The following information and reference articles are presented to provide the reader with some of the latest research to facilitate evidence-based, informed decisions regarding the use of conventional as well as CAM treatments.

 

For medical-legal reasons, access to these links is limited to patients enrolled in an Accurate Clinic medical program.

 

Should you wish more information regarding any of the subjects listed – or not listed –  here, please contact Dr. Ehlenberger. He has literally thousands of published articles to share on hundreds of topics associated with pain management, weight loss, nutrition, addiction recovery and emergency medicine. It would take years for you to read them, as it did him.

 

For more information, please contact Accurate Clinic.

 

Supplements recommended by Dr. Ehlenberger may be purchased commercially online or at Accurate Clinic.

Please read about our statement regarding the sale of products recommended by Dr. Ehlenberger.

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